Simparica Trio chewables for dogs (sarolaner, moxidectin, pyrantel) 24 mg/tab blue vs NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Overall winner: Simparica Trio chewables for dogs (sarolaner, moxidectin, pyrantel) 24 mg/tab blue
Key Differences
NexGard (B0DYGDMCYX) is a single-purpose flea & tick chewable with an appealing beef flavor and is positioned at a more affordable price tier; it’s FDA-approved to help prevent Lyme disease. Simparica Trio (B0DV9Y3X2K) provides broader parasite coverage—heartworm, ticks, fleas and intestinal worms—in one monthly chew and is approved for young puppies but is perceived by some customers as more expensive
Simparica Trio chewables for dogs (sarolaner, moxidectin, pyrantel) 24 mg/tab blue
Chewable tablet combo for dogs, protects against heartworms, ticks & fleas, and intestinal worms. Approved for puppies 8 weeks and older weighing at least 2.8 lb. One dose provides heartworm protection in studies supporting FDA-approval. Customers noted easy administration and rapid effect
Pros
- combination parasite protection
- easy to administer
- effective against fleas and ticks
- suitable for puppies 8 weeks+
Cons
- price considered high by some customers
- some customers question value
- ngial: limited data on other potential side effects
NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Flea and tick preventive chews for dogs, easy beef-flavor palatable. FDA-approved to prevent Lyme by killing ticks; effective against fleas and ticks for a month. Customer note: easy to use and well-valued
Pros
- beef-flavored chews for easy administration
- kills fleas and ticks all month
- FDA-approved to help prevent Lyme infections
- safe for dogs and puppies as young as 8 weeks
Cons
- prescription dog medication category
- requires monthly administration
- specific weight range covered per package
Head-to-Head
| Criteria | Winner |
|---|---|
| Price | Nexgard |
| Durability | Tie |
| Versatility | Simparica Trio |
| User Reviews | Tie |