Simparica Trio chewable tablets for dogs (3 mg) - 2.8-5.5 lbs vs NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Overall winner: Simparica Trio chewable tablets for dogs (3 mg) - 2.8-5.5 lbs
Key Differences
NexGard (A) is a beef-flavor monthly chew designed specifically to kill fleas and ticks and is FDA-approved to help prevent Lyme disease; it also lists a lower price tier. Simparica Trio (B) offers broader multi-parasite protection including heartworm prevention alongside flea and tick control but is presented in a higher price tier and some customers perceive it as expensive
Simparica Trio chewable tablets for dogs (3 mg) - 2.8-5.5 lbs
Chewable parasite prevention for dogs combining heartworm, ticks & fleas, and intestinal worm protection. Suitable for puppies 8 weeks+ and 2.8 lb+. Customers note quick effectiveness and easy administration
Pros
- 3-in-1 parasite protection
- Easy to administer
- Effective against fleas and ticks
- Approved for small puppies
Cons
- Mixed perception on value
- Some consider price high
NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Flea and tick preventive chews for dogs, easy beef-flavor palatable. FDA-approved to prevent Lyme by killing ticks; effective against fleas and ticks for a month. Customer note: easy to use and well-valued
Pros
- beef-flavored chews for easy administration
- kills fleas and ticks all month
- FDA-approved to help prevent Lyme infections
- safe for dogs and puppies as young as 8 weeks
Cons
- prescription dog medication category
- requires monthly administration
- specific weight range covered per package
Head-to-Head
| Criteria | Winner |
|---|---|
| Price | Nexgard |
| Durability | Tie |
| Versatility | Simparica Trio |
| User Reviews | Tie |