Simparica Trio chewable tablets for dogs (72 mg) vs NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Overall winner: Simparica Trio chewable tablets for dogs (72 mg)
Key Differences
NexGard (A) is a single-month beef-flavor chewable that targets fleas and ticks and is noted for preventing Lyme disease, while Simparica Trio (B) offers 3-in-1 parasite protection including heartworm protection and kills six types of ticks. Choose NexGard if you want a palatable monthly flea-and-tick chewable with strong customer liking; choose Simparica Trio if you need broader parasite coverage (heartworm plus multiple tick types)
Simparica Trio chewable tablets for dogs (72 mg)
Chewable monthly parasite protection for dogs covering heartworms, ticks & fleas, and intestinal worms. Effective at preventing fleas and ticks; easy for dogs to eat like a treat
Pros
- 3-in-1 parasite protection
- Effective heartworm protection demonstrated
- Kills six types of ticks
- Puppies as young as 8 weeks eligible
Cons
- Some customers regard it as expensive
NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Flea and tick preventive chews for dogs, easy beef-flavor palatable. FDA-approved to prevent Lyme by killing ticks; effective against fleas and ticks for a month. Customer note: easy to use and well-valued
Pros
- beef-flavored chews for easy administration
- kills fleas and ticks all month
- FDA-approved to help prevent Lyme infections
- safe for dogs and puppies as young as 8 weeks
Cons
- prescription dog medication category
- requires monthly administration
- specific weight range covered per package
Head-to-Head
| Criteria | Winner |
|---|---|
| Price | Nexgard |
| Durability | Tie |
| Versatility | Simparica Trio |
| User Reviews | Tie |