Simparica Trio chewable tablets for dogs 12 mg vs NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Overall winner: Simparica Trio chewable tablets for dogs 12 mg
Key Differences
NexGard (A) is a beef-flavor monthly chew for dogs 24.1–60 lbs and lists in a more affordable price tier; it emphasizes flea and tick protection and is FDA-approved to help prevent Lyme disease. Simparica Trio (B) is positioned as a 3-in-1 parasite protection chewable (adds heartworm prevention) and is noted as a premium-priced option that covers more parasite types
Simparica Trio chewable tablets for dogs 12 mg
Chewable monthly preventive for dogs combining sarolaner, moxidectin, and pyrantel. Protects against heartworms, ticks & fleas, and intestinal worms. Customers note effective prevention and easy administration
Pros
- three-category parasite protection
- dog-friendly chewable form
- approved for puppies 8 weeks and older
- demonstrated heartworm protection in studies
Cons
- some customers find it expensive
- varying perceptions of value
NexGard (afoxolaner) Flea and Tick Chewables for Dogs 24.1–60 lbs
Flea and tick preventive chews for dogs, easy beef-flavor palatable. FDA-approved to prevent Lyme by killing ticks; effective against fleas and ticks for a month. Customer note: easy to use and well-valued
Pros
- beef-flavored chews for easy administration
- kills fleas and ticks all month
- FDA-approved to help prevent Lyme infections
- safe for dogs and puppies as young as 8 weeks
Cons
- prescription dog medication category
- requires monthly administration
- specific weight range covered per package
Head-to-Head
| Criteria | Winner |
|---|---|
| Price | Nexgard |
| Durability | Tie |
| Versatility | Simparica Trio |
| User Reviews | Tie |